2018-2019 Undergraduate Catalog [ARCHIVED CATALOG]
Course Descriptions
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This section of the Catalog includes course descriptions, listed alphabetically by discipline. The descriptions provide information on course numbers, titles, the level of instruction, credit, course sequence, content, and prerequisites as shown in the following example:
CHE 2100 Introduction to Organic and Biological Chemistry
Credits: 5
Prerequisite: CHE 1100
Description: A study of the elements of organic and biological chemistry. This course satisfies requirements for nursing programs and other fields requiring a survey of organic and biological chemistry.
The first two to four letters, called the course subject code, represent the area of study or discipline, e.g., CHE represents chemistry. The course number follows the course subject code, e.g., 2100. The first digit in a four-digit course number designates the level of instruction. Only courses numbered 1000 or above will be included in credits toward a degree. Courses with numbers up to and including 1999 are primarily for freshmen, 2000 through 2999 primarily for sophomores, 3000 through 3999 primarily for juniors, and 4000 through 4999 primarily for seniors. In general, students should not take courses above the level of their class (based upon semester hours earned), but they may do so at one level above if they have the specified prerequisites. In special cases, students may be permitted to take courses more than one level above that designated for their class if they obtain the permission of their advisor and of the faculty member teaching the course and if they meet the prerequisite requirements. Course descriptions provide a summary of the content of the course. If a prerequisite must be met before a student can register for a course, this information is listed above the course description. Attributes, such as Multicultural, General Studies, or Guaranteed Transfer, are listed after the course description. A list of courses being offered in a given semester, instructors, class meeting times, and locations is described in the Class Schedule.
Types of Courses
- Regular courses appear in this section of the University Catalog and are offered on a regular basis.
- Independent study courses provide students the opportunity to pursue in-depth study of a topic of special interest. Independent study courses are specified as 498_ and include an alpha character in the course number. Independent study courses are published in the Class Schedule.
- Special topics or omnibus courses are temporary courses that are not listed in the Catalog. They may be used to pilot-test a course, present a special topic, or provide a unique, experiential-learning opportunity. Omnibus courses use a specified range of course numbers: 190_, 290_, 390_, 490_ and include an alpha character in the course number. Omnibus courses are published in the Class Schedule.
- Variable topics courses allow courses of varying titles under an overall theme or “umbrella” course. Variable topic courses include an alpha character in the course number and are published in the Class Schedule.
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Aviation and Aerospace Science |
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AES 2330 - Precision Flight and Navigation
Credits: 3
Prerequisite(s): AES 1100 or Private Pilot certificate
Description: The first Flight Team course prepares students for participation in the National Intercollegiate Flying Association regional and national flying meets. Flight and ground event accuracy and time events are learned. This course is required for students who are new members of the MSU Denver Precision Flight Team.
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AES 2500 - Instrument Flight
Credits: 1
Prerequisite(s): AES 1100 and Permission of instructor
Description: This course is designed to enable a student to obtain credit for earning an FAA Instrument rating under either Federal Aviation Regulations Part 61 or Part 141. A minimum of 40 hours of instrument flight time is required and course credit is contingent on the student obtaining the FAA Instrument rating.
Note: This course cannot be certified for veteran benefits.
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AES 2710 - Instrument Flight Simulation II
Credits: 3
Prerequisite(s): AES 2120
Description: This course covers instrument flight planning, navigation, and situational awareness during departure, enroute, and arrival phases of flight. Simulated flights include air traffic control (ATC) clearances, use of radio aids for determining position, holding patterns, and both precision and non-precision approaches. Pilot procedures during emergency and abnormal conditions are introduced and practiced.
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AES 3000 - Aircraft Systems and Propulsion
Credits: 3
Prerequisite(s): AES 1100 or FAA Private Pilot certificate, and PHY 1250 or Permission of instructor
Description: Introduces aircraft nomenclature, design, features, systems, and their components. Covers the theory, components, instrumentation, and operation of internal combustion and turbojet engines, as well as fuel, electrical, hydraulic, and pneumatic aircraft systems.
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AES 3040 - Unmanned Aircraft Systems Data Collection and Analysis
Credits: 3
Prerequisite(s): Junior Standing, or Permission of Instructor
Description: This course is an introduction to the techniques and processes that are needed to collect data from unmanned aerial vehicles (UAV). Students will learn how to acquire, process, and analyze data from photographic, multispectral, infrared, and LiDAR sensors. Students will receive class lecture and practical experience with sensors and processing applications. Topics include principles of data acquisition, aircraft and sensor selection, mission planning, data processing and analysis. Opportunities for applied practicum, including field trip work setting activities are provided.
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AES 3220 - Aviation and Aerospace Law
Credits: 3
Prerequisite(s): AES 1100 and Junior or Senior Standing
Description: This course provides an overview of fundamental aviation and space law. Concepts and terminology of constitutional law, administrative law, contract, and tort law as they relate to governmental organization, regulatory and international organizations, the regulatory environment, and regulation enforcement are highlighted. Principles of aviation liability and protections against liability claims are analyzed. Basic principles of space law are presented.
Note: Credit will be granted for only one prefix: AES or HON.
Cross Listed Course(s): HON 3220
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AES 3230 - Airline Management
Credits: 3
Prerequisite(s): Junior or Senior Standing or Permission of Instructor
Description: This course presents airline management issues, including the history and current organization of the airline industry, its economic impact on the society, and major management issues airlines face today. Discussions of the airline industry’s unique legal history, airline company organization, labor relations, airline financing, and international aviation are included.
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AES 3240 - Airline Planning
Credits: 3
Prerequisite(s): Junior or Senior Standing, or Permission of Instructor
Description: This course presents airline management issues, including the history and current organization of the airline industry, its economic impact on the society, and major management issues airlines face today. Discussions of the airline industry’s unique legal history, airline company organization, labor relations, airline financing, and international aviation are included.
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AES 3330 - Intermediate Precision Flight and Navigation
Credits: 2
Prerequisite(s): AES 2330
Description: The second Flight Team course is a continuation of AES 2330, further preparing the students for participation in the National Intercollegiate Flying Association regional and national flying meets. Flight and ground event accuracy and timed events are practiced with emphasis on speed as well as accuracy. Required for students who are second semester members of the MSU Denver Precision Flight Team.
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AES 3340 - Advanced Precision Flight and Navigation
Credits: 1
Prerequisite(s): AES 3330
Description: The third Flight Team course is a continuation of AES 3330, further preparing the student for participation in the National Intercollegiate Association regional and national flying meets. Flight and ground event accuracy and timed events are practiced with emphasis on speed as well as accuracy. Students at this level will help teach newer team members. It is required for students who are third semester members of the MSU Denver Precision Flight Team.
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AES 3460 - Weather for Aircrews
Credits: 3
Prerequisite(s): AES 1400, At least junior standing or Permission of instructor
Description: This course builds upon the basic aviation weather knowledge required of pilots with particular emphasis on those aspects of weather affecting advanced flight operations. Stability and turbulence, clear-air turbulence, icing, jet stream weather and the use of airborne radar are considered. Weather-related aircraft accident reports with analysis of the influence of the weather factors involved are reviewed in detail. Students will develop the ability to project their knowledge of weather to conditions at airports in unfamiliar locations.
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AES 3520 - Commercial Flight
Credits: 1
Prerequisite(s): FAA Private Pilot certificate and Permission of instructor
Description: The course is designed to enable a student to obtain credit for earning the FAA Commercial Pilot certificate under either Federal Aviation Regulations Part 61 or Part 141. Course credit is contingent on the student obtaining the FAA Commercial Pilot certificate.
Note: This course cannot be certified for veteran benefits.
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AES 3530 - Aerodynamics
Credits: 3
Prerequisite(s): PHY 1250 or PHY 2010
Description: This course studies the basic principles of aerodynamics, including airfoil shapes and aerodynamic forces, airplane performance, stability and control, strength limitations, and the application of these to specific flight situations. Included in this course are flight performance with air flow in the sub-, trans-, and supersonic envelopes.
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AES 3550 - FAA Instructor Certification-Ground School
Credits: 4
Prerequisite(s): AES 2130 or FAA Commercial/Instrument Certificate
Description: This course prepares the student to take the FAA Certified Flight Instructor knowledge examinations. Topic areas include advanced aeronautics, regulations, complex aircraft systems, and aeronautical decision-making concepts. Emphasis is placed on the practical aspects of flight instruction to include the preparation of lesson plans, presentation techniques, and evaluation principles.
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AES 3570 - Ground Instructor Practicum
Credits: 2
Prerequisite(s): FAA Commercial/Instrument certificate, CFI or Advanced or Instrument Ground Instructor certificate, or Permission of instructor
Description: This course provides students practice as aviation instructors in advanced single-engine flight simulators. It covers all aspects of flight planning and preparation, setup of simulators, cockpit management, and IFR and VFR flight procedures, and navigation.
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AES 3600 - Space Flight Operations I
Credits: 3
Prerequisite(s): At least junior standing or Permission of instructor
Description: Students review the history of space exploration and related issues motivating human inquiry and travel in space. Topics focus on identifying and understanding elements and systems comprising modern space vehicles and missions. Students analyze various national policies, treaties, and international laws affecting space operations. Fundamentals of interplanetary travel, orbit prediction, and launch and reentry operations are also investigated.
Note: Credit will be granted for only one prefix: AES or HON.
Cross Listed Course(s): HON 3602
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AES 3650 - Advanced Flight Technologies
Credits: 4
Prerequisite(s): AES 2120 and AES 2710 or an Instrument Rating
Description: The course is designed to emphasize advanced instrument procedures, including the use of global positioning system (GPS) and other area navigation (RNAV) systems. Additionally the course will cover pilot systems management concepts applicable to modern, technologically advanced, general aviation aircraft cockpits.
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AES 3710 - Multi-Engine Flight Simulation I
Credits: 3
Prerequisite(s): FAA commercial/instrument certificate or Permission of instructor
Description: This course introduces multiengine aircraft operations, such as IFR cross-country flight. Introduces complex weight and balance computations and use of performance charts. Normal and emergency procedures are studied in the twin-engine simulator. Aeronautical decision making and cockpit resource management are developed.
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AES 3850 - Human Factors and Physiology of Flight
Credits: 3
Description: At least junior standing Human factors, physiological effects and problems associated with flight are studied in this course This includes both high- and low-altitude flight environments
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AES 3870 - Aircraft Accident Investigation
Credits: 3
Prerequisite(s): At least junior standing or Permission of instructor
Description: This course examines techniques and procedures for investigating aircraft accidents/incidents and report writing. Areas of emphasis are operations, air traffic control, meteorology, witnesses, human factors, cockpit voice recorders, structures, power plants, systems, performance, maintenance records, and flight data recorders.
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AES 3880 - Aviation Security
Credits: 3
Prerequisite(s): Junior Standing, or Permission of Instructor
Description: The history, development and strategies of prevention and response to aviation security issues are studied in this course. The role of international and national agencies, including statutes and regulations are detailed, with particular emphasis on Transportation Security Regulations as they apply to airports and aircraft operators. The history of air terrorism is addressed, focusing on terrorist threats and governmental responses before and after 9/11/2001.
Note: Credit will be granted for only one prefix: AES or CJC.
Cross Listed Course(s): CJC 405M
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AES 3980 - Internship in Aviation and Aerospace Science
Credits: 1-15
Prerequisite(s): Major in aviation management or aviation technology; junior or senior status; permission of instructor
Description: Supervised by a faculty member within the major department, internships provide practical, hands-on experience in a professional field related to the major. Internship placements must be established prior to enrollment in this course in consultation with the Applied Learning Center.
Internship requirements vary by department. For information and instructions on finding and enrolling in an internship, contact the Applied Learning Center at 303-615-1333 or internships@msudenver.edu.
Note: Variable Credit
Course Revised July 3, 2018
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AES 4040 - Aircraft Performance
Credits: 3
Prerequisite(s): AES 1100, AES 3530 and At least junior standing
Description: Performance of jet- and propeller-powered aircraft is examined. Flight profiles are studied, with emphasis on aircraft capabilities, limitations, and determination of speeds, power, or thrust settings for various conditions of flight. Weight and balance performance charts are reviewed.
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AES 4100 - Advanced Air Traffic Control
Credits: 3
Prerequisite(s): AES 1400, AES 1800, AES 2200;or permission of instructor
Description: This course introduces advanced air traffic control topics in the areas of the National Airspace System; ATC teamwork; FAA Orders, Manuals, Letters of Agreement and Standard Operating Procedures; separation standards; airspace; flight principles and rules; navigation; charts; approaches; emergencies; search and rescue; weather principles and reporting; ATC communications; clearances; and strip marking. Students will reinforce learning using ATC simulation.
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AES 4200 - Airport Planning and Management I
Credits: 3
Prerequisite(s): At least junior standing or Permission of instructor
Description: This course introduces airport planning, management, and operations concepts. Topics covered include air traffic, forecasting, sources of revenues and expenses, management of revenue- producing facilities, and the U.S. Federal Aviation Administration regulations dealing with airport operations and security. Current problems with environmental impact, land use planning and control, airport capacity and delay, public relations, airport finance, airport privatization, liability, and economic impact are introduced.
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AES 4210 - Airport Planning and Management II
Credits: 3
Prerequisite(s): Senior Standing, AES 4200, or permission of instructor
Description: This is an advanced course in airport planning, management, and operation. At the conclusion of the course, students will be able to apply fundamental management theory to airports, determine airport capacity, and assess the potential for delays; evaluate airport environmental impacts; and identify components of the National Airspace System and its relationship to airports. They will be able to apply financial management and accounting techniques to airport finances, set airport fees, rates, and charges, and understand the process for obtaining capital funding for airport improvements. Evaluation and use of airport master plans, state airport system plans, and airport layout plans are also covered, as well as basic principles of terminal design and operations, applicable Federal Aviation Regulations, airport security, and basic airport emergency response procedures. Successful completion of the course prepares the student for the Certified Member (C.M.) of the American Association of Airport Executives (AAAE) examination.
University Requirement(s): Senior Experience
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AES 4230 - General and Business Aviation Operations
Credits: 3
Prerequisite(s): Senior standing or Permission of instructor
Description: This course is a study of the general aviation service industry (fixed-base operators and specialized aviation service operators). The course includes lectures on the history and evolution of the general aviation service industry, management functions, marketing, finance, human resources, operations, and safety.
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AES 4240 - Air Cargo Industry
Credits: 3
Prerequisite(s): Junior Standing
Description: An overview of the air cargo industry, including the size and scope of the industry, market segmentation, the role of air freight forwarders, economics and pricing of services, air cargo aircraft design and technology, management issues in the industry, and transportation of hazardous materials.
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AES 4370 - Advanced Navigation Systems
Credits: 3
Prerequisite(s): AES 2120 and 60+ credits
Description: This course is a follow-up to the navigation portion of AES 1100 and AES 2120. The student explores geographic coordinate systems, short-range and long-range route navigation, and aircraft position determination with systems available in modern aviation. Electronic instrumentation, navigation and flight management systems (FMS), electronic flight instrumentation systems (EFIS), inertial navigation systems (INS) and global positioning systems (GPS) are discussed.
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AES 4500 - Flight Multi-Engine
Credits: 1
Prerequisite(s): FAA Commercial Pilot certificate and Permission of instructor
Description: This course covers multi-engine aircraft operations. A minimum of 10 hours of flight training time are required. The FAA multiengine rating must be obtained to receive credit for this course.
Note: This course cannot be certified for veteran benefits.
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AES 4510 - Flight Instructor
Credits: 1
Prerequisite(s): FAA Commercial/Instrument Pilot certificate and Permission of instructor
Description: This course provides the basic aeronautical knowledge and flight experience necessary for the FAA Certified Flight Instructor certificate. Fifteen hours of flight training are required and the FAA Certified Flight Instructor certificate must be obtained to receive credit for this course.
Note: This course cannot be certified for veteran benefits.
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AES 4520 - Flight Instructor-Instrument
Credits: 1
Prerequisite(s): FAA Certified Flight Instructor certificate and Permission of instructor
Description: This course provides the basic aeronautical knowledge and experience that the instrument flight instructor must have. Ten hours of flight training are required and the FAA Instrument Instructor rating must be obtained to receive credit for this course.
Note: This course cannot be certified for veteran benefits.
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AES 4530 - Flight Instructor-Multi-Engine
Credits: 1
Prerequisite(s): CFI, multi-engine rating and Permission of instructor
Description: This course provides the basic aeronautical knowledge and experience relative to multiengine flight instruction that the prospective multi-engine flight instructor must have. Fifteen hours of flight training time is required. The FAA Multi-Engine Flight Instructor rating must be obtained to receive credit for this course.
Note: This course cannot be certified for veteran benefits.
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AES 4550 - Flight Helicopter
Credits: 1
Prerequisite(s): Permission of instructor
Description: Helicopter systems, aerodynamics, flight characteristics, helicopter operations, and pertinent regulations and procedures are studied in this course. The FAA Commercial Pilot certificate with the Rotorcraft-helicopter rating must be obtained to receive credit for this course.
Note: This course cannot be certified for veteran benefits.
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AES 4570 - Airline Transport Pilot
Credits: 1
Prerequisite(s): FAA Commercial/Instrument certificate and Permission of instructor
Description: Fifteen hundred hours of flight time, including 500 cross-country, 100 hours night flying, and 75 hours of instrument flight are required to complete this course. Students should be close to having completed the required flight hours before enrolling in this course. The course involves knowledge of navigation, weather, FARs, radio communications, weight distribution on aircraft and loading. Course credit is contingent on the student obtaining the FAA Airline Transport Pilot certificate.
Note: This course cannot be certified for veteran benefits.
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AES 4580 - Turbojet Flight Engineer or Type Rating
Credits: 4
Prerequisite(s): FAA Flight Engineer Knowledge examination and/or Permission of instructor
Description: This course is for the student with access to type rating or flight engineer training, such as at an airline, and consists of ground school for B-727, DC-8, or other turbojet airplanes. Approximately 15 hours of second officer or “type” training and a flight check in the airplane or an FAA-approved simulator will be completed at a facility external to the college.
Note: This course cannot be certified for veteran benefits.
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AES 4590 - Flight Instructor Practicum
Credits: 2
Prerequisite(s): AES 3570, FAA Commercial/Instrument certificate, CFI, Advanced or Instrument Ground Instructor certificate, or Permission of instructor
Description: This course provides students practice as a flight instructor in advanced single- and twin-engine flight simulators. It covers all aspects of flight planning and preparation, setup of simulators, cockpit management, IFR flight procedures and navigation, and emergency procedures using the capabilities of the simulator computers.
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AES 4601 - Space Flight Operations II
Credits: 3
Prerequisite(s): AES 3600
Description: Advanced issues related to space operations are investigated in this course. Topics include payload and spacecraft design, bioastronautics, spacecraft control systems, and launch vehicles. Emphasis is placed on current and proposed space transportation systems, space stations, and planetary exploration. Students practice principles of orbital mechanics and related calculations applied to operational management of space vehicles and space stations.
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AES 4602 - Aerospace Commercialized Operations
Credits: 3
Prerequisite(s): AES 4601
Description: This course explores past, current, and proposed business ventures focused on creating commercial opportunities in space. Students will consider factors of risk associated with conducting space business. Case-based analyses and projects designed to understand and conceptualize potential new commercial space organizations will be conducted within the class.
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AES 4603 - Aerospace Operations Systems Analysis and Design
Credits: 3
Prerequisite(s): AES 4601
Description: Students are introduced to concepts related to conceptualizing, designing, and integrating commercial space systems. Processes and analytical tools related to systems integration, systems engineering, and operational management are included. Students learn mathematical techniques for assessing risks, optimization, and design trade-offs commonly used by commercial operations in the space industry.
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AES 4607 - Orbital Mechanics and Aerospace Systems Simulations
Credits: 3
Prerequisite(s): MTH 1110; AST 1040 or PHY 2010; or permission of instructor
Description: Students will be introduced to orbital analysis using Analytical Graphics Inc (AGI)’s Systems Tool Kit (STK) software. They will integrate this analysis with simulations involving ground systems, ground vehicles, aircraft and ships. Students will use STK to assess, risks, optimize performance, and develop alternatives. The main purpose of the course is to introduce STK software, its interface and capabilities related to orbital mechanics concepts.
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AES 4610 - Aerodynamic Design
Credits: 3
Prerequisite(s): AES 3530, or permission of instructor
Description: Students analyze aerodynamics in both the subsonic and supersonic range. Airfoil theory, the calculations of lift and drag, National Advisory Committee for Aeronautics (NACA) derived airfoils, and their applications will be studied. A wind tunnel laboratory is utilized to conduct experimentation with the Bernoulli equation and Reynolds number and to test aerodynamic properties of various structures.
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AES 4710 - Turboprop Flight Simulation
Credits: 4
Prerequisite(s): AES 2710; Senior standing; FAA Private Pilot certificate with instrument rating; Commercial Pilot Certificate; and Multiengine rating or AES 3710
Description: This course introduces twin-engine turboprop aircraft operations. Skill is developed in weight and balance computations and use of performance charts. Normal and emergency procedures are studied specific to turboprop airplane operations. Aeronautical decision-making and crew resource management skills are developed. Procedures used in regional air carrier operations are covered.
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AES 4860 - Aviation Safety
Credits: 3
Prerequisite(s): Junior Standing
Description: This course provides an overview of the modern approach to aviation safety. Included are analyses of the framework and operation of safety regulations, the role of the National Transportation Safety Board, key safety definitions and statistics, human factors in safety, air traffic safety issues, aircraft safety systems, airline safety programs, and safety management systems. The focus is on understanding causal and contributing factors to aircraft accidents and incidents and developing risk management, and organizational and regulatory strategies to improve safety.
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AES 4870 - Aviation Safety Program Management
Credits: 3
Prerequisite(s): Completion of all required 3000-level AES courses and Senior standing
Description: This course addresses requirements to develop comprehensive safety programs for aviation organizations at aviation facilities. Included are the philosophy of operations and support of air transportation; the dynamics of interpersonal relationships; Quality Assurance (QA) and Quality Control (QC); effective communications techniques; correct procedures for handling FAA, NTSB, and OSHA investigations and reports; and effective proactive management to obtain federal legislation in support of accident prevention, safety, and health programs. Federal Emergency Management Agency (FEMA) emergency planning and Disaster Recovery planning are covered. Emphasis is placed on the management of aviation safety programs.
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AES 4910 - Aviation and Aerospace Strategic Planning
Credits: 3
Prerequisite(s): Aviation and Aerospace Management or Science Major and junior standing or permission of instructor
Description: This capstone course requires the student to demonstrate and have critiqued their knowledge, skills, and critical thinking abilities in strategic planning as applied to current topics in aviation and aerospace science. Students must demonstrate analytical and interpretive abilities, along with professional level communications skills. Emphasis is placed on decision making ability applied to the aeronautical or aerospace discipline of choice. Students are mentored in industrial trends, best practices, and regulatory issues that address modern industry challenges. Students are further prepared through a professional development certificate process and must develop a career plan and portfolio for assessment by the instructor.
Note: Credit will be granted for only one prefix: AES or HON.
University Requirement(s): Senior Experience
Cross Listed Course(s): HON 4910
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AES 4930 - Professional Flight Standards Seminar
Credits: 3
Prerequisite(s): Senior status, AES 300, AES 4040, and the FAA Commercial Pilot Certificate with Instrument Rating
Description: This course is a senior level capstone course for Aviation Technology majors. It is an academic survey of Crew Resource Management, organizational communication, aviation psychology, strategies, principles and contemporary issues in aviation with a practical emphasis on advanced cockpit automation.
University Requirement(s): Senior Experience
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AES 4935 - Advanced Commercial Aircraft Systems
Credits: 4
Prerequisite(s): Senior Standing, AES 3000, AES 3530, AES 4040, and the Commercial Certificate with Instrument Rating
Corequisite(s): AES 4930
Description: This course gives the air carrier first officer candidate an operational knowledge of modern, air carrier, aircraft systems. This includes powerplant, fuel, electrical, hydraulic, pneumatic. air conditioning, pressurization, avionics, flight controls, fire protection, and ice and rain protection systems. It also provides instruction in normal, irregular, and emergency procedures.
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AES 4950 - Aviation and Aerospace Science Management Strategies
Credits: 3
Prerequisite(s): Completion of, or concurrent enrollment in, all other Aviation and Aerospace Science core courses and Senior standing
Description: This capstone course presents a progression of aviation and aerospace management case based studies designed to emphasize the application of team building, communication, and critical thinking skills in the work environment. Students are required to synthesize and apply their knowledge and skills to each case. The skills and knowledge acquired by students throughout their education in the Aviation and Aerospace Science Department are evaluated in this course.
University Requirement(s): Senior Experience
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Beverage Management |
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BVG 2015 - Beverage Fundamentals
Credits: 3
Description: This course provides an overview of responsible beverage service. Practical handson experience focuses on how to manage the beverage option of a restaurant, hotel and event business and its relationship to sustainable tourism. Students learn the requirements to equip, staff, manage, and market beverage operations. Classroom activities allow for student appraisal and evaluation of the preparation and service of beverages. Course assignments and activities provide a review of the major commercially available beverages of the world to build student awareness of the procurement and selection of quality beverages for hospitality operations.
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BVG 2350 - Brewery Mechanics
Credits: 3
Description: Students are introduced to multi-craft tasks associated with brewery operation and maintenance. Students engage in an overview of mechanical, electrical, plumbing, HVAC, and cleaning systems identification and operation. Preventative maintenance, sanitation standards, safe handling of equipment, and movement of product and ingredients through the brewing process will also be covered.
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BVG 3010 - Beers of the World
Credits: 3
Prerequisite(s): Students must be at least 21 years of age.
Description: This course is an overview of the beer styles of the world. The development of beer styles includes the historical, environmental and cultural influence of global beer regions. Global beer styles are analyzed through sensory analysis and evaluating the presentation and service of beers and their accompanying foods. The components of beer, manufacturing techniques and cultural influences on beer styles will provide a framework for understanding beer style. Classic beer styles in the current American craft brewing industry will be examined.
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BVG 3220 - Beer and Food
Credits: 3
Prerequisite(s): HTE 1533 or RST 1550
Description: In this course, students will study the proper use of professional kitchen equipment to prepare recipes that emphasize beer as the key ingredient. Kitchen and restaurant laboratory activities emphasize the techniques and principles of cooking that enhance the interaction of beer and food when prepared, served and tasted together. The student will be introduced to the various cooking methods of foods and how preparation effects the interaction with beer. Students experience the planning, service, and cost analysis of beer and food pairing menus in a professional restaurant setting.
Note: All students must present valid ID in order to be served alcohol. Students under the age of 21 years may taste, but not consume alcohol under the State of Colorado “Sip and Spit” law (18-13-122, C.R.S., 12-47-801 C.L.C) and comply with department consumption policies.
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BVG 3350 - Brewery Operations
Credits: 3
Prerequisite(s): ACC 1010 or ACC 2010
Description: Students will be introduced to the principles of brewery management that are critical to planning, operation and sustainment of a successful brewing operation. Students will formulate plans for creating a distinctive brand and managing the key aspects of brewery operations, legal requirements, equipment, supplies, maintenance, and safety of a successful brewery and tasting room.
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BVG 3613 - Wine Fundamentals
Credits: 3
Description: This course is designed for the student who wishes to learn the basics of wine knowledge for personal gratification as well as to serve the student who expects to have a professional interest in the selection and service of wine. Viticulture, vinification, service and critical appraisal of wines of the major wine regions of the world are covered.
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BVG 3683 - Beer and Spirits
Credits: 3
Description: This course provides a practical experience of brewing beer and distilling spirits. Course activities enhance an understanding of the scientific and technical aspects of malting, brewing, fermenting, finishing, and conditioning beer. Spirit distillation activities extend upon scientific and technical brewing and fermentation to include the steps in the distillation process and aging of spirits. Students engage in sensory analysis of global beer and spirit styles to gain perspective on the level of quality and aspects of style apparent in commercial brands.
Note: All students must present valid ID in order to be served alcohol. Students under the age of 21 years may taste, but not consume alcohol under the State of Colorado “Sip and Spit” law (18-13-122, C.R.S., 12-47-80 I C.L.C) and comply with department consumption policies.
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BVG 3750 - Alcohol Beverage Law
Credits: 3
Description: In this course students are introduced to the concepts and information regarding legally creating and selling alcohol in Colorado and the United States. Students will delve into the complex and ever-changing world of brewery licensing, alcohol distribution laws, city zoning, real estate contracts and proper labeling and selling of beer, spirits and wine. Furthermore, students will learn the basics of creating a corporation or company and becoming legally compliant to sell beer through both a tasting room and through off-premises accounts such as liquor stores and restaurants. This class will focus on Colorado laws, however, all 50 states will be covered so students are prepared to work around the country. Upon completion, students will be able to feel confident in avoiding pitfalls and errors commonly seen with startup breweries.
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BVG 3810 - Sensory Quality Analysis of Beer
Credits: 3
Prerequisite(s): MTH 1210 and Student much be at least 21 years of age.
Description: In this course students are introduced to the microbiological and chemical principles that lead to aromatic and taste expressions in beer. Students develop and practice procedures for sensory evaluation of beer. The appropriate uses of specific tests are discussed, along with physiological, psychological, and environmental factors affecting sensory verdicts. Upon completion of the course, students are expected to be able to formulate methodology for addressing the test objectives, statistically analyze test results, draw conclusions and make test recommendations. Specific quality analysis of beer faults are practiced in classroom and sensory classroom exercises.
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BVG 3950 - Beverage Promotion
Credits: 3
Description: Students are introduced to the principles of selling and brand marketing of beverage products. Students focus on relationship building, communication and sales promotion in the context of a wide range of alcoholic and nonalcoholic beverages. Students develop an understanding of brand identity and strategies to communicate corporate vision and product value to customers.
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BVG 4000 - Applied Brewing Operations
Credits: 3
Prerequisite(s): Minimum 90 credit hours completed; BVG 3010; BVG 3350; BVG 3750 and BVG 4350
Description: In this course, students apply the theoretical concepts of brewing, distributing and alcoholic beverage brand management to a practical learning experience. The course includes 45 hours of field experience in a practicum, community volunteer program, or study-abroad setting. Students synthesize related literature and theory to apply artisanal craft and science to the development of a brewing project. Following product design or business management practices, students apply current tenets of management to position a product for market distribution or to examine management control systems. External assessment of student designed beers, packaging and distribution plans are reviewed with industry partners to verify student expertise and mastery of the art and science of beer design, management principles, production, marketing, and distribution.
University Requirement(s): Senior Experience
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BVG 4010 - Beer Styles and Service
Credits: 3
Prerequisite(s): BVG 3010
Description: In this course, students will study the recognized beer styles common of traditional and modern interpretations of worldwide beer regions. The cultural history and the interaction of local customs in the production and service of regional beers is an important aspect of beer style. In-depth sensory analysis of appropriate aromas, foam, color, and tastes of beers are reviewed in open and blind tastings. Recognition of faults common in beer brewing are an integral component to laboratory activities, including production and storage flaws, as well as aspects of service that enhance and detract from beer quality. Draft systems and appropriate design, operation, and maintenance of direct draw, pump, and mixed gas systems are reviewed and practiced in laboratory settings.
Note: All students must present valid ID in order to be served alcohol. Students under the age of 21 years may taste, but not consume alcohol under the State of Colorado “Sip and Spit” law (18-13-122, C.R.S., 12-47-801 C.L.C) and comply with department consumption policies.
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BVG 4220 - Brewing Fermentation
Credits: 3
Prerequisite(s): BIO 2400, BVG 4350
Description: Students are introduced to an overview of the modern and traditional brewing fermentation processes. Laboratory activities and assignments complement course activities related to the microbiology of fermentation and brewing with yeast. The techniques of brewing with yeast are reviewed and executed by students to highlight appropriate management systems for fermentation in a brewery. Students ferment, bottle, keg, and serve several batches of beer in different manners, with different microorganisms, and at different scales to harness a dynamic skill set. The collection, storage, and handling of yeast in the brewery are reviewed to maximize performance of yeast and their corresponding flavor produced in beer.
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BVG 4350 - Brewing Science
Credits: 3
Prerequisite(s): BIO 2400, CHE 2100
Description: The course applies brewing science principles in a laboratory setting. The selection of water, grains, hops, and adjunct ingredients illustrate how plant physiology, biochemistry, and microbiology relate to the brewing of beer. Class laboratory activities provide practical application of the principles of beer style selection, malting, brewing, cooling, fermentation, aging, and packaging of beer. The quality of beer is illustrated throughout the brewing process, including the relative environmental impact and outcomes of commercial brewing.
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BVG 4613 - Wines of the Old World
Credits: 3
Description: In this course, students will examine the old world wine regions of Europe. Students will compare and contrast major historical and cultural events that have given shape to these vineyards and created a strong wine culture. There is a strong emphasis on the growing and harvesting logistics of location as well as climate and heritage. Class discussion is complemented by tastings of selected wine groups.
Note: All students must present valid ID in order to be served alcohol. Students under the age of 21 years may taste, but not consume alcohol under the State of Colorado “Sip and Spit” law (18-13-122, C.R.S., 12-47-801 C.L.C) and comply with department consumption policies.
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BVG 4623 - Wines of the New World
Credits: 3
Description: In this course students critically examine the agricultural and wine making characteristics that create unique wine styles in emerging regions, known as the new world of wine. Regional analysis includes wines from the Americas, Africa, and Australasia. Extensive evaluation of new world wines through blind tasting provides a measure of student evaluation of wine components unique to their regional classification. Tours of local wineries provide oppo1tunities to examine and inspect the production methods of various styles of wine.
Note: All students must present valid ID in order to be served alcohol. Students under the age of21 years may taste, but not consume alcohol under the State of Colorado “Sip and Spit” law (18-13-122, C.R.S., 12-47-801 C.L.C) and comply with department consumption policies.
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BVG 4633 - Wine and Food
Credits: 3
Prerequisite(s): HTE 1533 or RST 1550
Description: In this course students practice evaluation of wines and begin to analyze how wines interact with foods. examine specific interaction of food and wine components and how each interacts to create foundations of taste. Critical analysis of food and wine pairing includes the preparation of foods, menu and recipe development with an understanding of flavor of food and wine and how their architecture relates to the dining experience. Practical inrestaurant service techniques and hands-on food production will be appraised as well as critical reviews of wine lists and food and wine pairings. A gourmet dinner service activity will provide practical application for food preparation relating wine pairing sand service skills.
Note: All students must present valid ID in order to be served alcohol. Students under the age of 21 years may taste, but not consume alcohol under the State of Colorado “Sip and Spit” law (18-13-122, C.R.S., 12-47-801 C.L.C) and comply with department consumption policies.
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BVG 4810 - Brewing Quality Analysis
Credits: 3
Prerequisite(s): BVG 4350
Prerequisite(s) or Corequisite(s): BVG 4220
Description: This course addresses the science of beer quality. The various impacts on the perception of beer quality from raw ingredient selection, handling, processing, packaging, and service of beer are reviewed through detailed class lecture and laboratory experience. The biochemical and hedonistic evaluation of beer quality at all stages of production and service are practiced in laboratory and service settings in order to manage quality attributes of beer and how they can be delivered to the consumer. The course is vital to brewing production managers who aim to account for the science of beer appearance, flavor, stability and wholesomeness.
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BVG 4950 - Enology: The Making of Wine
Credits: 3
Prerequisite(s): HTE 3613 or BVG 3613 or Approval of Instructor
Description: In this course, students will study winemaking principles, including, harvest, crushing, pressing, wine microorganisms, fermentation, and operations. Topics include wine making in both traditional and nontraditional methods, cap management, yeast and malolactic inoculation, wine microbes, barrel aging, racking, filtration and bottling. Coursework integrates lecture, field visits to vineyards and wineries, and hands-on winemaking.
Note: All students must present valid ID in order to be served alcohol. Students under the age of 21 years may taste, but not consume alcohol under the State of Colorado “Sip and Spit” law (18-13-122, C.R.S., 12-47-801 C.L.C) and comply with department consumption policies.
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BIO 398A - Internship in Medicine
Credits: 1-12
Prerequisite(s): Major in biology; junior or senior status; permission of instructor
Description: Supervised by a faculty member within the major department, internships provide practical, hands-on experience in a professional field related to the major. Internship placements must be established prior to enrollment in this course in consultation with The Internship Center.
Internship requirements vary by department. For information and instructions on finding and enrolling in an internship, contact the Applied Learning Center at 303-615-1333 or internships@msudenver.edu.
Note: Variable Credit
Course Revised July 3, 2018
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BIO 398B - Internship in Nursing
Credits: 1-12
Prerequisite(s): Major in biology; junior or senior status; permission of instructor
Description: Supervised by a faculty member within the major department, internships provide practical, hands-on experience in a professional field related to the major. Internship placements must be established prior to enrollment in this course in consultation with The Internship Center.
Internship requirements vary by department. For information and instructions on finding and enrolling in an internship, contact the Applied Learning Center at 303-615-1333 or internships@msudenver.edu.
Note: Variable Credit
Course Revised July 3, 2018
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BIO 1000 - Human Biology for Non-Majors
Credits: 3
Prerequisite(s): Minimum performance standard scores on reading, writing, and mathematics preassessment placement tests
Description: This one-semester course familiarizes the student with the principles of the living world, the basic form and function of the human body, and how these two relate to each other. Basic variations of life forms, and the interrelationships of the human body to the surrounding world are the main thrusts of the course.
Note: This course does not apply toward a biology major or minor.
General Studies: Natural and Physical Sciences
Guaranteed Transfer: GT-SC2
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BIO 1030 - General Biology for Non-Majors
Credits: 4
Description: This one-semester course familiarizes the student with the principles of the living world at all levels ranging from molecules to ecosystems. Basic similarities and differences in cellular mechanisms, organismal organization, and ecological processes are identified, with focus placed on the evolutionary principles that interconnect all forms of life including humans. This course does not apply toward a biology major or minor.
General Studies: Natural and Physical Sciences
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BIO 1080 - General Biology I
Credits: 3
Prerequisite(s): Minimum performance standard scores on reading, writing and mathematics preassessment placement tests
Corequisite(s): BIO 1090
Description: This introductory course serves as the foundation for all other biology courses. Emphasis is placed on cellular and molecular biology, biochemical pathways, and genetics.
Note: Credit will be granted for only one prefix: BIO or HON. A student must successfully pass both BIO 1080 and BIO 1090 to receive General Studies and GT-SC1 credit.
General Studies: Natural and Physical Sciences
Guaranteed Transfer: GT-SC1
Cross Listed Course(s): HON 1080
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BIO 1081 - General Biology II
Credits: 3
Prerequisite(s): BIO 1080 and BIO 1090; or permission of instructor
Corequisite(s): BIO 1091
Description: This course is a continuation of General Biology I (BIO 1080). Coursework emphasis is placed on evolution, ecology, and the classification, diversity, and structure of plants and animals.
Note: A student must successfully pass both BIO 1081 and BIO 1091 to receive General Studies and GT-SC1 credit.
General Studies: Natural and Physical Sciences
Guaranteed Transfer: GT-SC1
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BIO 1090 - General Biology Laboratory I
Credits: 1
Prerequisite(s): Minimum performance standard scores on reading, writing and mathematics preassessment placement tests
Corequisite(s): BIO 1080
Description: This mandatory laboratory accompanies BIO 1080. This course introduces biology laboratory techniques, specifically exploring the scientific method.
Note: Credit will be granted for only one prefix: BIO or HON. A student must successfully pass both BIO 1080 and BIO 1090 to receive General Studies and GT-SC1 credit.
General Studies: Natural and Physical Sciences
Guaranteed Transfer: GT-SC1
Cross Listed Course(s): HON 1090
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BIO 1091 - General Biology Laboratory II
Credits: 1
Prerequisite(s): BIO 1080 and BIO 1090; or permission of instructor
Corequisite(s): BIO 1081
Description: This mandatory laboratory accompanies BIO 1081. This course will explore and reinforce concepts introduced in BIO 1081 through laboratory and field exercises in ecology, evolution and diversity.
Note: A student must successfully pass both BIO 1081 and BIO 1091 to receive General Studies and GT-SC1 credit.
General Studies: Natural and Physical Sciences
Guaranteed Transfer: GT-SC1
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BIO 2100 - General Botany
Credits: 5
Prerequisite(s): BIO 1080 and BIO 1090, BIO 1081 and BIO 1091 or Permission of instructor
Description: This is a one-semester introductory survey of the plant kingdom with an emphasis on evolutionary theory, life cycles, anatomy and morphology, and vascular plant physiology.
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BIO 2310 - Human Anatomy and Physiology I
Credits: 4
Prerequisite(s): BIO 1080 and BIO 1090 or Permission of instructor
Description: This is the first of two courses addressing the structure and function of the human body. Topics include tissues, anatomy, the musculoskeletal system, and neurophysiology. Course content and level are designed for allied health science students and for human performance and sport or recreation professions majors.
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BIO 2320 - Human Anatomy and Physiology II
Credits: 4
Prerequisite(s): BIO 2310 or Permission of instructor
Description: This is the second of two courses addressing the structure and function of the human body. Topics include endocrinology; circulation; and the respiratory, digestive, urinary and reproductive systems. Course content and class level are designed for allied health science students and for human performance and sport or recreation professions majors.
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BIO 2400 - General Microbiology
Credits: 5
Prerequisite(s): BIO 1080 and BIO 1090, BIO 1081 and BIO 1091, one semester of college chemistry, or Permission of instructor
Description: This is a one-semester introduction to the microbial world, including discussions of bacteria, Cyanobacteria, fungi, protozoans, and viruses.
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BIO 3000 - Advances in Biology
Credits: 3
Prerequisite(s): BIO 1080 and BIO 1090 and CHE 1800 or Permission of instructor
Description: The course examines the impact of modern science and technology on the future development of biological science. Topics include space and diving physiology, the impact of the information revolution (computers and the Internet), the science of exobiology, new techniques to study biology, directions in modern medicine, and nanotechnology.
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BIO 3020 - Laboratory Techniques
Credits: 2
Prerequisite(s): BIO 1080, BIO 1081, BIO 1090, BIO 1091 or permission of instructor
Prerequisite(s) or Corequisite(s): CHE 1800
Description: This laboratory course provides experience performing laboratory techniques in molecular biology. Topics include a review of basic laboratory skills, preparation of buffers, use of instrumentation and advanced techniques such as cell fractionation, electrophoresis, and PCR.
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BIO 3050 - Cell and Molecular Biology
Credits: 4
Prerequisite(s): BIO 1080 and BIO 1090, BIO 1081 and BIO 1091, or permission of instructor
Prerequisite(s) or Corequisite(s): CHE 3100 or CHE 2100, or permission of instructor
Description: This course is an intensive study of the eukaryotic cell, cellular structure, and organization. Emphasis is placed on the molecular mechanisms underlying cell functions, including intracellular transport and transport across membranes, cytoskeletal proteins and cellular motility, metabolic pathways and energy production, photosynthesis, cell cycle and cellular growth, cell signaling pathways, and stem cells.
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BIO 3120 - Economic Botany
Credits: 4
Prerequisite(s): BIO 2100; or permission of instructor
Description: This course investigates the diversity of plants and their relationships with man as food, fibers, chemicals, and medicines. Consideration will be given to plants useful or harmful to humans: their origins and history; botanical relationships; economically important chemical constituents; and their roles in prehistoric and modern cultures and civilizations.
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BIO 3140 - Plant Physiology
Credits: 5
Prerequisite(s): BIO 2100 or Permission of instructor
Description: This course is a comprehensive survey of the internal chemical changes within plants and how these changes control growth and development. Discussions include water relations, transpiration, food transport, ion uptake, photosynthesis, respiration, plant movements, flowering, dormancy, and senescence.
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BIO 3160 - Plant Anatomy and Morphology
Credits: 4
Prerequisite(s): BIO 2100 or Permission of instructor
Description: This course is a survey of cell types, tissue systems, and the anatomical structure of stems, roots, and leaves of vascular plants. The development and evolutionary history of vascular plants will be discussed.
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BIO 3170 - Paleobotany
Credits: 4
Prerequisite(s): BIO 2100
Description: This course examines the history of plant form and function as shown in the fossil record. The investigation of evolutionary relationships of modern plant groups unifies the course. Students consider the process of fossilization and techniques of reconstructing whole plants from fragmentary remains. A synthesis of biological and geological perspectives provides insights into the paleoecological relationships of the ancient communities in which these organisms lived. An introduction to the use of plant fossils in biostratigraphy and their roles in coal, oil and gas formation are considered. Class sessions include demonstrations, as well as frequent hands-on interaction with fossil plant specimens.
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BIO 3180 - Vascular Plant Taxonomy
Credits: 4
Prerequisite(s): BIO 2100 or Permission of instructor
Description: The identification and collection of the common vascular plants of Colorado is studied. Lectures include principles of plant terminology, characteristics of major plant families, phylogenetic relationships, and uses of the plants. Laboratories consist of identification of the plants in the field and on herbarium mounts. A student collection is required.
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BIO 3200 - Invertebrate Zoology
Credits: 4
Prerequisite(s): BIO 1080 and BIO 1090, BIO 1081 and BIO 1091, or Permission of instructor
Description: This course includes classroom, laboratory, and field study of phylogeny, structure, function, development, and conservation of invertebrate animals. The course emphasizes diversity, evolutionary changes, and adaptation to the environment. Topics range from the molecular to the ecological level of study.
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BIO 3210 - Histology
Credits: 4
Prerequisite(s): BIO 1080 and BIO 1090, and BIO 1081 and BIO 1091, or BIO 2310, or BIO 2320, or Permission of instructor
Description: A comprehensive study of the microscopic structure and appearance of body tissues and of the tissue composition of body organs, mainly as seen in mammals. Emphasis is placed on the laboratory. Correlations are drawn between structure and function. Laboratory drawings and digital images are required.
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BIO 3220 - Comparative Vertebrate Anatomy
Credits: 5
Prerequisite(s): BIO 1080 and BIO 1090, BIO 1081 and BIO 1091, or Permission of instructor
Description: A comprehensive study is made of the evolution of structure and function of vertebrates. The laboratory portion of the course is emphasized and will consist of detailed dissections of vertebrates representing several classes.
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BIO 3230 - Principles of Human Anatomy and Physiology for Secondary Education
Credits: 5
Prerequisite(s): BIO 1080/BIO 1090 or Permission of instructor
Description: This course addresses the structure and function of the human body. Topics include homeostasis, tissues, the musculoskeletal system, neurophysiology, endocrinology, circulation, and respiratory, digestive, urinary, and reproductive systems. Course content and class level are designed only for students who are biology majors seeking licensure in secondary science education.
Note: This course will not count for biology credit for any other biology majors and will not substitute for BIO 2310 and BIO 2320.
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BIO 3240 - Animal Behavior
Credits: 4
Prerequisite(s): BIO 1080, BIO 1081, BIO 1090, and BIO 1091
Description: This course serves as an in-depth and current account of the interdisciplinary science of Animal Behavior. Beginning with a review of both historical and modern approaches, behavioral psychology and behavioral ecology will be comprehensively examined with an emphasis on evolution. The accompanying laboratory will highlight scientific methodology by incorporating both descriptive and experimental studies of Animal Behavior in laboratory and field settings.
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BIO 3260 - Vertebrate Zoology
Credits: 4
Prerequisite(s): BIO 1080 and BIO 1090, BIO 1081 and BIO 1091 or Permission of instructor
Description: This course examines the origin, evolution, classification, morphology and adaptation of the vertebrates.
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BIO 3270 - Parasitology
Credits: 4
Prerequisite(s): BIO 1080 and BIO 1090, BIO 1081 and BIO1091, BIO 3200, and At least junior standing
Description: This course covers the identification, life cycles, host-parasite relationships, and epidemiology of protozoan, platyhelminth, nematode, acanthocephalan, and arthropod parasites important in human and veterinary medicine.
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BIO 3280 - Field Ornithology
Credits: 2
Prerequisite(s): BIO 1080, BIO 1090, BIO 1081, BIO 1091, and permission of instructor
Description: This is a comprehensive course on the field aspects of ornithology. Students will learn proper identification techniques and methods for conducting independent research in the area of avian behavior, conservation and ecology.
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BIO 3300 - Advanced Human Biology for Non-Majors
Credits: 3
Prerequisite(s): BIO 1000 or permission of instructor; and completion of General Studies requirements in Written Communication, Oral Communication, and Quantitative Literacy.
Description: This course is designed to be an advanced sequel to BIO 1000. It addresses the more complex aspects of human body functions and how the body deals with insults such as bombardment of microorganisms, various dietary practices, pollution, and socio-economic challenges. Topics include immunity, AIDS, genetics, stress, cancer, and aging.
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BIO 3320 - Advanced Human Physiology
Credits: 4
Prerequisite(s): BIO 1080 and BIO 1090, BIO 2310, BIO 2320, one year of chemistry
Description: This in-depth physiology course covers the function of the human body as it relates to homeostasis. This course emphasizes membrane transport, fluid compartments, acid-base balance, cardiovascular and respiratory physiology, and neurotransmission.
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BIO 3330 - Advanced Human Cadaver Anatomy
Credits: 5
Prerequisite(s): BIO 1080, BIO 1090, BIO 2310, and upper-division standing. BIO 2320 is recommended.
Description: This course presents human gross anatomy from a regional perspective, using clinical applications as a basis for anatomical understanding. Designed for biology majors entering professional and graduate schools.
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BIO 3340 - Endocrinology
Credits: 3
Prerequisite(s): BIO 1080 and BIO 1090, BIO 1081 and BIO 1091, two additional semesters of biology, and CHE 3100, or Permission of instructor
Description: This course is a survey of the major human endocrine organs and their hormones. Topics include normal anatomy and physiology of each gland, cellular mechanisms of hormone action, and endocrinopathies.
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